Blackwell Reference Online

Extract

Formulation Method Dilution Rate Comments Compatibility Hyoscine butylbromide (scopolamine butylbromide) Ampoule 20 mg/1 mL Buscopan Boehringer Ingelheim (UK) IV bolus NPSA risk rating: 2 Ready diluted. May be further diluted to a convenient volume with NS or G Over at least 1 minute Infusion-related adverse events : hypersensitivity, skin reactions, shortness of breath, tachycardia, hypotension, dizziness, flushing, injection site pain after IM administration pH : 3.7‑5.5 (undiluted) Osmolality : 272 mOsmol/kg Flush : N S Sodium content : 0.3 mmol/1 mL vial Other comments : for further information about the use of hyoscine in palliative care refer to local syringe driver guidelines Compatible fluids : NS, G, GS Compatible in a syringe for (C) SC infusion : cyclizine , dexamethasone , diamorphine , fentanyl , haloperidol lactate , levomepromazine , metoclopramide , midazolam , morphine , octreotide , ondansetron , oxycodone See Supplementary material 15 for further details IM NPSA risk rating: 2 Ready diluted Bowel colic in palliative care : (C) SC infusion via a syringe driver (unlicensed) NPSA risk rating: 6 Dilute to a convenient volume with NS or W May be mixed with other drugs in the same syringe See comments Adults : usually 20‑60 mg over 24 hours Children : usually 40‑60 micrograms/kg over 24 hours • ... log in or subscribe to read full text